Phenotypic suppression of the motility defects of unc-54(r293) after RNAi. smg-1(+) indicates a wild-type allele of smg-1. smg-1(0) indicates a null allele that expresses no detectable SMG-1 protein. smg-1(cc546ts) is a temperature-sensitive allele of smg-1 that is defective for NMD at 25°C and competent for NMD at 20°C. All strains, except wild-type, contain rrf-3(pk1426) in addition to the indicated smg-1 and unc-54 mutations.
| Genotype | RNAi | Phenotype (20°C) |
| Wild type | None | Normal motility |
| smg-1(+) unc-54(r293) | None | Paralyzed |
| smg-1(0) unc-54(r293) | None | Normal motility |
| None | Paralyzed | |
| smg-2 | Normal motility | |
| smg-1(cc546ts) unc-54(r293) | smg-8 | Partial motility |
| ruvb-1 | Partial motility | |
| ruvb-2 | Partial motility | |
| smg-10 | Partial motility |