Table 3 Amino acid sequences of intracellular loop and C-terminal region peptides.

All listed peptides were linked with a TAT sequence (YGRKKQRRR). The numbers indicate the peptide location in the mPanx1 amino acid sequence. The CT1 peptide has previously been published to inhibit NMDA-mediated Panx1 opening (21).

Amino acid sequence (mPanx1)
IL1178-VGQSLWEISE-187
IL2191-KYPIVEQYLK-200
CT1305-RRLKVYEILPTFDVLH-318
CT2381-IPTSLQTKGE-390
Scrambled IL2IYLYVEQKPY