Table 2 Micromolar IC₅₀ values for XMD17-109 in different ECs.

n.d., no data.

Agonist	HUVECs		HMVEC-lung cells
Agonist	IL-6	IL-8	IL-6	IL-8
Pam3Cys
10 μg/ml	0.38	0.39	0.39	0.45
FSL-1
10 μg/ml	2.02	1.83	0.82	0.79
LPS
10 μg/ml	0.80	0.74	0.66	1.17
1 μg/ml	1.37	1.88	0.68	0.96
TNF-α
10 ng/ml	0.61	2.63	0.43	0.59
IL-1β
10 ng/ml	3.46	3.68	n.d.	n.d.
1 ng/ml	3.26	1.98	0.58	0.67
0.1 ng/ml	0.58	0.63	0.41	0.48
Average IC₅₀	1.56	1.72	0.57	0.73