Table 4 Single AP waveform characteristics of neurons exposed to CTL versus CTL + apamin and RG108 versus RG108 + apamin in Fig. 7.

All values are means ± SEM. *P < 0.05, Student’s t test. n, number of cells.

Treatment (n)CTL (8)CTL + apamin (5)RG108 (10)RG108 + apamin (4)
AP waveform
Vthr (mV)−45.1 ± 1.049.0 ± 0.9−49.1 ± 0.6−47.3 ± 2.1
Maximal depolarization rate (mV/ms)75.0 ± 4.278.2 ± 3.780.7 ± 4.573.0 ± 8.8
Amplitude (mV)73.0 ± 2.478.3 ± 2.579.0 ± 2.072.8 ± 4.7
Maximal repolarization rate (mV/ms)33.8 ± 3.828.4 ± 4.534.0 ± 3.428.5 ± 4.5
One-half width (ms)2.3 ± 0.12.8 ± 0.42.4 ± 0.22.5 ± 0.2
fAHP (mV)−13.5 ± 0.9−10.6 ± 1.2−9.4 ± 3.2−11.3 ± 2.4
mAHP (mV)−22.7 ± 0.4−17.5 ± 1.3*17.0 ± 1.117.3 ± 2.2
Time-to-peak (ms)40.3 ± 3.737.6 ± 3.041.1 ± 3.043.0 ± 2.8