Table 4 Estimated cause-specific and subdistribution HRs for relapse and death of other cause using unadjusted and adjusted regression models.

	Cox: Cause-specific HR
	Relapse		Death of other cause
	HR (95% CI)	P	HR (95% CI)	P
CHEK1 unadjusted	2.11 (1.31–3.39)	0.002	1.39 (0.55–3.52)	0.49
CHEK1 adjusted*	2.32 (1.41–3.80)	0.001	1.26 (0.47–3.34)	0.65
	Fine-Gray: Subdistribution HR
	Relapse		Death of other cause
	HR (95% CI)	P	HR (95% CI)	P
CHEK1 unadjusted	1.97 (1.23–3.18)	0.005	1.31 (0.52–3.33)	0.56
CHEK1 adjusted*	2.19 (1.32–3.65)	0.003	1.20 (0.42–3.40)	0.73

*Adjusted for year of diagnosis, age, sex, white blood cell count, and cytogenetic risk group.