Table 1 Summary of fitted curve parameters for inhibition of cAMP accumulation.

EC50, pEC50, and Emax values with SEM are given for Fig. 1B.

RANTESMIP-1α5P125P146P4PSC
CCR5
  EC50 (nM)0.712.10.40.10.4
  pEC50 ± SEM−9.2 ± 0.19−9.0 ± 0.26−8.7 ± 0.38−9.4 ± 0.22−9.9 ± 0.31−9.4 ± 0.56
  Emax ± SEM26 ± 2.320 ± 2.518 ± 3.231 ± 3.120 ± 3.014 ± 3.4